It happened Saturday, in fact, for the first time since Sept. 11, 1976.
These proud programs have 19 combined Associated Press national titles, but the fan bases are generally not the types to sip tea and wait for storms to blow over.
Let's take a dispassionate step back, though, and try to analyze each situation. We'll offer hope and inspiration (where possible).
Crisis, or not a crisis?
This is a football DEFCON 1.
The good news is the school dumped Coach Kiffin and got significantly better on that side of the ball. Unfortunately, the coach was Monte and the side was defense.
USC's defense under first-year coordinator Clancy Pendergast is a big upgrade from the creamy-filling soft Tampa 2 concepts.
Trojans fans, though, are demanding relief from the entire Kiffin royal family following Saturday's 10-7 home loss to Washington State. Boos are raining down on the Coliseum the way ash once did on the old Trojan hamlet of Pompeii.
I admit to having the wrong Lane Kiffin tipping point, figuring it would come with an intolerable home loss to Utah State on Sept. 21.
What now? The problem is Athletic Director Pat Haden, an honorable man of his word, recently made a video 100% backing the same Lane Kiffin who backed USC into 7-6 last year.
Don't expect Haden to overreact just because fans are dissatisfied. That won't happen unless USC loses next week to Boston College.
Time capsule: USC lost on Sept. 11, 1976, to Missouri. It was John Robinson's first game as coach and he received so much hate mail the Carrier Pigeons' Union went on strike. USC rebounded with 11 straight wins that included a Rose Bowl win over Michigan.
Notre Dame (Not a Crisis)
The Irish, big deal, fell short in a highly entertaining game at Michigan. This may be a good time to reiterate Notre Dame was never going 12-0 again on its way to the BCS title game. Last year was as fluky as it was fun with Notre Dame pulling out one harrowing win after another.
The loss of quarterback Everett Golson to academics terminally doomed the repeat odds as hope was placed again on senior Tommy Rees, a talented but turnover-prone quarterback whose two interceptions Saturday in the 41-30 loss were the 35th and 36th of his career.
Time capsule: Notre Dame lost to Pittsburgh on Sept. 11, 1976. The Panthers were 12-0 that season on their way to the national title. Notre Dame finished 9-3 under Dan Devine with a win over Penn State in the Gator Bowl.
Mack Brown said he'd have to take a look at the film before deciding whether defensive coordinator Manny Diaz deserved to be back for next week's Mississippi game.